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Sedation Vacations and Spontaneous Breathing Trials

A “sedation vacation” or “spontaneous awakening trial (SAT)” is a period of sedation cessation during which a patient can be assessed to ensure they are receiving the proper level of sedation. The patient is first screened to ensure they meet the criteria for a SAT. If they meet the criteria for an SAT, sedation will be interrupted and the patient will be evaluated. If the patient tolerates the interruption in sedation, they will then proceed to a spontaneous breathing trial (SBT) safety screen and possibly a SBT.  Upon passing a SBT, extubation may be considered.

According to Balas et. al. (2011), performing SATs and SBTs on a daily basis led to “significant decreases in the duration of mechanical ventilation, shorter ICU stays, … and significantly fewer overall complications (eg, ventilator-associated pneumonia, upper gastrointestinal hemorrhage, bacteremia, barotrauma).” During my clinicals at Cottage Hospital I have only cared for one patient on a ventilator. I did not see a SAT and/or SBT performed on this patient, however looking at this patient retrospectively, I do not think they were hemodynamically stable enough to pass the safety screening. I have yet to have a clinical rotation in the MICU or SICU so I am looking forward to learning more about the hospital’s use of SATs and SBTs during that rotation.

I was able to access and review Cottage Hospital’s policy for their daily awakening trial/weaning protocol. The safety screening parameters and guidelines for SATs and SBTs very closely followed the parameters cited by Balas et. al. (2011) but were slightly more conservative. One thing Balas et. al. (2011) mentioned that I found interesting was “use of the ABCDE bundle should not depend on an individual physician’s order but rather should be structured as a daily part of care with clearly defined safety guidelines (e.g. an “opt-out” rather than “opt-in” approach to care delivery)”. In both the SAT and SBT safety screening policies Balas et. al. (2011) cited, the provider was prompted to include every patient unless they met an “opt out” parameter. Looking at the safety screening protocol for Cottage Hospital, the policy for SATs is written to include all patients unless contraindicated, but the policy for SBTs was written to include only those patients that meet specific parameters. I am curious to know if the language used in the policy affects the amount of patients that are appropriately screened. Using “opt-out” safety parameters may more effectively include patients that are eligible to be screened. It will be interesting to see the culture and practice surrounding SATs and SBTs when on the unit.

 

References:

Balas, M. C., Vasilevskis, E. E., Burke, W. J., Boehm, L., Pun, B. T., Olsen, K. M., … Ely, E. W. (2012). Critical Care Nurses’ Role in Implementing the “ABCDE Bundle” into Practice. Critical Care Nurse, 32(2), 35–48. http://doi.org/10.4037/ccn2012229
Shynk, T. (2010). Daily Awakening trial/Weaning Protocol in Mechanically Ventilated Patients, Cottage Hospital

Pharmacological Education at Home

Hi this is Breehan! person_with_pill_bottleBecause my mom just had a knee replacement, I talked to her about her different medications. She is on Percocet and Tramadol. I was surprised that her doctor did not educate her about not mixing the Percocet and Tramadol too closely together until she actually asked him after I told her that she should not take the maximum amount of each medication all at once, especially because she enjoys a glass of wine in the evening when she tends to take her pain medications to help her sleep. I warned her not to mix the wine and medications and explained why it was a bad idea.

 

Once my mom was educated about that, she was then confused about whether she could mix Ibuprofen with the opiates and I had to educate her that Ibuprofen and Percocet or Tramadol are ok together but to make sure not to take too much Acetaminophen along with the Percocet if she takes the maximum amount every 4-6 hours as is recommended on the bottle. Once again, I was so dismayed and surprised that my mom’s surgeon did not take the time to give her this important pharmacological education.

 

The surgeon did succeed at least in telling my mom about the side effects of being on strong opiate pain medication post-op. He encouraged her to take stool softeners for the constipation and not to drive while under the influence of the medications.

 

I was glad I was present to assist my mom in educating her about her medications and rather appalled that she had not been told what I considered very basic information about them in the post-op period.

 

 

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Sedation Vacation

I actually have not seen sedation vacation performed in clinicals, but I know Cottage has their own policy and procedure for conducting it. In Cottage, the nurse and Respiratory Therapist collaborate to perform sedation vacation according to the optimal time based on the pt and family’s schedule. In order for the procedure to be performed, the pt must not meet any absolute or relative contraindications. Absolute contraindications includes increased ICP that is exacerbated with awakening or if pt is less than 18 yrs old. Relative contraindications include: PEEP greater than or equal to 10cm H20, PaO2/FiO2 less than or equal to 200, SpO2 less than 90% on FiO2 greater than or equal to 50%. If pt does not meet any contraindications, then all sedation infusions are turned off and pt is assessed according to the Richmond Agitation Sedation Score (RASS). Hospital protocols are then performed according to assessment thereafter.

Standard practice for sedation vacation is the same as Cottage Hospital. Many researchers encourage and promote sedation vacation because of its benefits to the pts (Dunn and Baker, 2011). These include less ICU stays, less chances of developing ICU delirium, and decrease need for ventilator support (Dunn and Baker, 2011). The medications used by Cottage include Lorazepam, Propofol, and Midazolam. If the pt does fail the RASS, then 50% of the previous sedation dose is infused and titrated accordingly. Hospital protocols are followed thereafter.

Reference:

Santa Barbara Cottage Hospital Daily Awakening Trial/Weaning Protocol in Mechanically Ventilated Patients

Dunn, J., Baker, M.W. (2011). Daily Sedation Breaks and Breathing Trials Help Wean Patients from Ventilators Safely: The Authors Give Advice on Developing a Nurse-Implemented Sedation Protocol. American Nurse Today, 6(3). Retrieved from: http://www.medscape.com/viewarticle/741046_6

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Sedation Vacation

Sedation Vacation Blog

 

I did not know much about sedation vacation so it was interesting for me to read the blogs of other students. I also found an article that talks about educating the nurses. This article helped me understand this process and the reasons for it to be performed. Sedation vacation is also called daily sedation interruption and can be beneficial for mechanically ventilated patients (Hogue & Mamula, 2013). Critically ill patients often need continuous IV sedation with analgesia since they may experience pain from mechanical ventilation, suctioning, surgical incisions, catheters, etc. Sedation is required to assess patient’s neurologic status and determine the necessity for further sedation. Hogue and Mamula state that evidence based practice recommends interrupting sedation at least daily in mechanically ventilated patients (2013). Some of the benefits include the ability to accurately titrate sedation, which allows to reduce the time on mechanical ventilation, length of ICU stay, lower risk for ventilator associated pneumonia, etc. (Hogue & Mamula, 2013).

The article also suggests a short quiz on testing your knowledge about the Sedation Vacation. They did not provide the answers, but you guys seem to know so much about this intervention that you can probably figure them out!

1.How long should DSI last?

a.10 minutes

b.20 minutes

c.until patient follows commands

d.until patient exhibits agitation

e.c and d

2.Circle all common benefits of daily sedation interruption.

a.decreased length of time of ventilation

b.decreased length of ICU stay

c.increased sedation

d.decreased other complications, such as ventilator-associated pneumonia and central line-associated bloodstream infection.

e.decreased anxiety

3.Which isn’t a potential adverse reaction to DSI?

a.psychedelic dreams

b.self-extubation

c.pain

d.anxiety

e.rebound agitation

4.DSI is better for acute posttraumatic stress disorder.

a.true

b.false

5.Do you think DSI is important for your patients?

a.yes

b.no

 

References

Hogue, M., & Mamula, S. (2013). Sedation vacation: Worth the trip. Nursing Critical Care, 8(1), 35-37.

 

Sedation Vacay

tim-teuscher-2I had never encountered the term sedation vacation before my time in the SICU last week. My nurse did bring up the term in educating me and said that it is used on critical patients such as the patient with a TBI I had on Thursday who was on long-term heavy sedation with Versed, Fentanyl, and Propofol, while intubated in the ICU to give her various body systems a break from the physiological effects of the sedatives. It also allows the nurse to perform a neurovascular check, as well as reducing the risk of ventilator acquired pneumonia and ICU delirium as well as assessing the patient’s readiness to extubate, which is the ultimate goal. I asked my nurse if, when they were given the sedation vacation, they were disturbed by the ventilator.

 

I imagined that if I were awakened suddenly out of a foggy sedation and found myself on a ventilator, I would be very disturbed. The nurse assured me that the patients were not fully awakened and so that was not a problem.

 

My nurse explained that ideally the sedation vacation is performed by a multidisciplinary team consisting usually of the nursing, respiratory, pharmacy, and the primary intensive care unit team. It is ideally done daily or once a shift. It can only be performed on patients who are hemodynamically stable enough to tolerate the vacation. These patients must also not show agitation, be properly oxygenated, not have very much secretions, and normal respirations under 38 per minute (ICU Sedation Guidelines of Care).

Patients are assessed for spontaneous breathing The Ramsey Scale which identifies six levels of sedation from severe agitation to deep coma is used. The Richmond Agitation and Sedation Scale is also used. It measures from light sedation to unarousable (ICU Sedation Guidelines of Care).

Sedation vacations, or daily sedation cessation trials have been found to reduce overall time on the ventilator, needed fewer diagnostic tests to examine neurologic function, had a better psychological adjustment and fewer instances of PTSD six months after their ICU stay (Dunn & Baker, 2011).

 

 

Dunn, J. & Baker, M.W. (2011). Daily Sedation Breaks and Breathing Trials Help

Wean Patients from Ventilators Safely. American Nurse Today 6(3). Retrieved from http://www.medscape.com/viewarticle/741046

 

ICU Sedation Guidelines of Care. (2009). Retrieved from

http://www.carefusion.com/pdf/The_Center/2009-ICU-sedation-toolkit-disclaimer-updated-may-30-2014.pdf

 

Sedation Vacation…What I’ve Learned :-)

“Sedation vacation” is an interesting  topic, one which I had not considered before it was recently brought up in class. I have spent two shifts in the SICU and witnessed patients on intubation and sedation, but unfortunately, in my clinical rotations I have not had the opportunity to see it during the course of a patient’s stay. It was a strong impression…seeing patients unconscious and not breathing on their own. From what I understand, many of these patients could be on ventilation and sedated indefinitely, so close monitoring and attention is important to better understand when they can be advanced to being weaned off of sedation, if possible.

Since this topic of sedation vacation was assigned after my opportunity to speak to the staff regarding the hospital protocols, I decided to take a closer look at hospital approved reading under Cottage Hospital’s “Nursing Resources”. I decided to focus my reading on the top three recommended articles available at Cottage to see what I could learn of interest…

I found that sedation vacation is also referred to as Daytime Awakening Trial (DAT), and has only recently been looked at for protocol creation in the last ten years. Interestingly, there is still limited research as to whether or not a primary nurse team or a collaborative team (respiratory therapist, physician, nurse and pharmacist) are more effective than the other. There is general agreement, however, that a dedicated ventilator bundle rounding team (VBR) in addition to the primary nurse team, is the most effective combination (Mendez et al. 2013).

Despite who performs the “bundle” of assessments, what is in agreement are the parameters checked for patients on sedation. Generally, the assessment occurs in the early morning (between 0500-0900), and five areas are performed and assessed as a bundle: sedation vacation, spontaneous breathing trial (SBT), head of the bed ≥30º, prophylaxis of deep vein thrombosis, and prophylaxis of peptic ulcer disease (PUD). For ongoing assessment of sedation, the  Richmond Agitation and Sedation Scale was used.

 

Upon closer reading, I noticed that ventilator-associated pneumonia is of great concern, as it is considered the second most common hospital acquired infection in the United States and is responsible for 25% of the infections that occur in intensive care units (Vallés, 2007). In response to this phenomenon, additional practices added to the bundle may include protocols for mouth care and hand washing, head-of-bed alarms and subglottic suctioning in addition to the DAT bundle protocol.

According to the articles, the patients who were found to be the most ready for sedation weaning included those with the following parameters: hemodynamic stability, minute ventilation less than 15 L/min, not hypoxic (PaO2 > 60 mm Hg, oxygen saturation > 92%, fraction of inspired oxygen <50%, positive end-expiratory pressure <5 cm H2O), minimal secretions, rapid shallow breathing index less than 120, and respiratory rate less than 38/min.

So, although I was not able to directly apply this week’s learning objective, sedation vacation, directly to my clinical experience, I am now more enlightened and feel that I understand and am better able to assist and collaborate in the new bundle protocols. Despite this assignment coming after my SICU shifts, I feel that I am now more informed on the generally accepted protocol and bundle for sedated patients and will apply what I learned for future patients’ cases.

One last comment I would like to share, is that in the cases where the patients were sedated, I witnessed the nurses speak to them as though they were alert, hearing and comprehending. This was of course most important when performing the neuro checks, but also showed great compassion and respect. I was impressed and think they deserve some recognition for their professionalism and humanity.

REFERENCES
Makic, M., Rauen, C., Jones, K., & Fisk, A. (2015). Continuing To Challenge Practice To Be Evidence Based. Critical Care Nurse, 35(2), 39-50.

Mendez, M., Lazar, M., Digiovine, B., Schuldt, S., Behrendt, R., Peters, M., & Jennings, J. (2013). Dedicated Multidisciplinary Ventilator Bundle Team and Compliance with Sedation Vacation. American Journal of Critical Care, 22(1), 54-60.

ICU Sedation Guidelines of Care. (2009, December 1). Retrieved October 3, 2015, from http://www.carefusion.com/pdf/The_Center/2009-ICU-sedation-toolkit-disclaimer-updated-may-30-2014.pdf

Sedwick, M., Lance-Smith, M., Reeder, S., & Nardi, J. (2012). Using Evidence-Based Practice to Prevent Ventilator-Associated Pneumonia. Critical Care Nurse, 32(4), 41-51.

Vallés, J., Pobo, A., García-Esquirol, O., Mariscal, D., Real, J., & Fernández, R. (2007). Excess ICU mortality attributable to ventilator-associated pneumonia: The role of early vs late onset. Intensive Care Med Intensive Care Medicine, 33(8), 1363-1368.

Collaborative Care with RT

In clinical, what are you seeing related to sedation vacation and collaboration with Respiratory Therapists? What is ideal? What is standard practice? What medications are you seeing in the clinical setting for sedation? What tools are used to determine the infusion rate?

In clinical the main areas I have witnessed collaboration with Respiratory Therapists (RTs) is my time in NICU, PICU, or when my patient in Med/Surg went into respiratory distress and we had to call rapid response. In the NICU, the RTs play a crucial role monitoring all of the neonates on vents and making changes as needed.

I haven’t witnessed sedation vacations on the floor, but it seems like a good concept to implement. When a patient is on a mechanical ventilator it can be uncomfortable and inadvertently inflict pain on the patient. Sedation is provided to give the individual a more pleasurable experience amongst the necessary equipment to monitor their well-being. The ideal practice is to provide a vacation or weaning from the sedation medications once a shift to assess neurological systems, ability to follow commands, and evaluate the need for remaining on sedation.

In the clinical setting the medications that I have most seen used are fentanyl and lorazepam.

To determine the infusion rate:

drug dose ordered (mcg) x patient’s weight (kg) x 60
drug concentration (mcg/mL)

You also want to know the target goal for sedation, times of sedation vacations, and how often neurological checks are to be performed.

Hogue, M., & Mamula, S. (2013). Sedation vacation: Worth the trip. Nursing 2015 Critical Care, 8(1), 35-37.

Mechanical Ventilation with Sedation

A few weeks ago I had a patient in the ICU who had been intubated and placed on a ventilator. This patient had critical aortic stenosis and was placed on a ventilator following an attempted right internal jugular line placement that resulted in a massive right hemothorax. On the day that I was in the ICU the physician and primary RN decided that they would taper the patient down off the Sublimaze (fentanyl) and Versed (midazolam) being used for analgesia and sedation. The team’s ultimate goal was to see if the patient was ready to be extubated. In addition, the patient was placed on CPAP as a trial. In this particular case it was very important that the patient be monitored for any signs of agitation or distress due to the fact that increased stress would activate the sympathetic nervous system and increase the workload on the heart. Due to the severe aortic stenosis and compromised cardiac function, an increase in workload would be poorly tolerated by the patient. By noon the patient started to respond to stimulation. The patient would open his eyes in response to voices and became agitated during suctioning and turning. The increased heart rate that accompanied the agitation required that the Sublimaze and Versed be initiated once again. Ultimately, the respiratory therapist, nurse, and physician agreed that based on the trial CPAP and spontaneous awakening trial, the patient was not ready to be extubated. Ventilation and sedation are often a necessary treatment for a person with severely compromised cardio-pulmonary function. Nonetheless, these treatments have to be used judiciously with constant reappraisal of the situation in order to minimize the potential short- and long-term consequences of ICU-acquired delirium and weakness. During my next ICU clinical I look forward to investigating the procedures and protocols that are instituted in the hospital units.