Renal GU Drug Review!
Group: Alyson Del Poso, Alex Bultman
Name: Bactrim
Who?
- UTI, Acute otitis media, chronic bronchitis, shigellosis, pneumonia, traveler’s diarrhea
What? Bactrim is a combo drug of 400mg sulfamethoxazole and 80mg trimethoprim.
- Classification: anti-bacterial sulfonamide
- both drugs inhibit bacteria’s ability to utilize folic acid
When?
- once daily
Where?
- acute AND chronic home med.
Why?
- inhibit bacteria’s growth by inhibiting the ability to utilize folic acid for growing
- bacteriacidal
How?
- PO – mild infections 6-12mg/kg/day
- PO – for UTI 160mg trimethoprim/800 sulfamethoxazole
- IV – 6-12mg/kg/day
- Safety: watch for sulfa allergy, monitor bowel function, monitor for s/s of Stevens Johnson Syndrome, CBC levels, urinalysis
